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Drug intelligence / Profile preview
[89Zr]Zr-DFO-AMI
- Development stage
- Unknown
- Lead developer
- University of Alabama at Birmingham
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Gamma Emitters → Radiopharmaceuticals
01
Overview
[89Zr]Zr-DFO-AMI: sourced facts only. name: "[89Zr]Zr-DFO-AMI specifically binds EGFR and c-MET." [DOI:10.1158/1538-7445.am2026-lb491]; target: "[89Zr]Zr-DFO-AMI specifically binds EGFR and c-MET." [DOI:10.1158/1538-7445.am2026-lb491]; target: "[89Zr]Zr-DFO-AMI specifically binds EGFR and c-MET." [DOI:10.1158/1538-7445.am2026-lb491]; developer: "University of Alabama at Birmingham, Birmingham, AL." [DOI:10.1158/1538-7445.am2026-lb491]; modality: "AMI was conjugated to p-SCN-Bn-deferoxamine (DFO) and radiolabeled with Zirconium-89 to generate [89Zr]Zr-DFO-AMI." [DOI:10.1158/1538-7445.am2026-lb491]
02
Targets
EGFR (Epidermal growth factor receptor)MET (Mesenchymal-epithelial transition factor receptor)
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